In Situ Forming Silk Fibroin Gel Kits

Short Description:

The lyophilized silk fibroin provided in the kit can be quickly dissolved into solution, which transforms into hydrogel after mixing with components provided in the kit using syringes and an adaptor provided.


Product Detail

Product Tags

凝胶推拉过程2222凝胶挤压过程450

Brand Name: Fancci

Alternative Name: Injectable silk fibroin hydroge

Introduction:

 The component A provided in the kit can be quickly dissolved into solution, which transforms into hydrogel after mixing with Component B and C using syringes and an adaptor provided. The gel preparation can either be conducted on site by the users themselves (in situ-forming), with the entire manipulation less than 5 min, or the gel can be prepared and pre-packed in syringes or tubes by the manufacturer so that it can be used directly. Depending on the applications, the in-situ forming hydrogel can be prepared in a concentration range 1-30%, thus ideal for encapsulation and delivery of cells and drugs for in vitro and in vivo studies.

Components of Kit

Components Properties Specifications Number Outer packing
Component A white bulk foam 0.3 g/vial 2 penicillin vial
Component B Colorless transparent liquid, Sterile
8 mL 1 penicillin vial
Component C Colorless transparent liquid, Sterile 8 mL 1 penicillin vial
Medical Luer adaptor Medical material / 1 Sterile sealing package
sterile syringe Sterile 20 mL 2 Sterile sealing package

Table 1 Parameter, testing and method of in situ forming silk fibroin gel Kits

Parameter, Testing and Method In situ forming silk fibroin gel Kits
Category Materials/Agents
Form Gel Kit
Source Degummed Bombyx mori silkworm
Method of storage  Storage in a dry, ventilated place at room temperature
Concentration range 1-30%
Gelling Time 30 min
Bioburden Sterilized ( per components )
Expiration Date 18 months

Application: 

  The in situ-forming and injectable silk hydrogel can be used as a drug and cell delivery carrier for researches in tissue engineering/repair and drug delivery. The drugs and cells to be delivered can be pre-mixed with regenerated silk fibroin solution and further mixed with other components provided in the kit to quickly form hydrogel. Silk hydrogel is distinguished from other biomaterial hydrogels by providing excellent mechanical strength, chemical and physical stability, biocompatibility and degradability. 




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