Mu Situ Ndimapanga silika Fibroin gel osakaniza zida

Short Description:

The lyophilized silika fibroin anapereka zida akhoza mwamsanga kusungunuka mu njira, amene amasintha mu hydrogel pambuyo kuyanjana ndi zigawo anapereka zida ntchito syringes ndi adaputala anapereka.


mankhwala Mwatsatanetsatane

Tags mankhwala

凝胶 推拉 过程 2222凝胶 挤压 过程 450

B Dzina rand: Fancci

Dzina njira ina: m'jekeseni silika fibroin hydroge

Kuyamba :

 Mbali A anapereka zida akhoza mwamsanga kusungunuka mu njira, amene amasintha mu hydrogel pambuyo kuyanjana ndi chigawo B ndi C ntchito syringes ndi adaputala anapereka. Kukonza gel osakaniza zikhonza kuchitikira pamalo ogwiritsa ntchito okha (mu situ-kupanga), ndi mpheto lonse osachepera 5, kapena gel osakaniza angathe kukonzekera ndi chisanadze ankanyamula mu syringes kapena machubu ndi Mlengi kotero kuti mungathe ntchito mwachindunji. Malinga ntchito, mu-situ kupanga hydrogel angathe kukonzekera mu ndende zosiyanasiyana 1-30%, motero abwino encapsulation ndi yobereka maselo ndi mankhwala mu m'galasi ndi maphunziro pompo-pompo.

C omponents ya zida

zigawo katundu zofunika Number akunja wazolongedza
chigawo A woyera chochuluka thovu 0,3 g / vial 2 Penicillin vial
chigawo B Colorless mandala madzi, wosabala
8 mL 1 Penicillin vial
chigawo C Colorless mandala madzi, wosabala 8 mL 1 Penicillin vial
Medical Luer adaputala zakuthupi Medical / 1 Wosabala kusindikiza phukusi
wosabala syringe wosabala 20 ml 2 Wosabala kusindikiza phukusi

Table 1 chizindikiro, kuyezetsa ndi njira ine N situ kupanga silika fibroin gel osakaniza zida

Chizindikiro, kuyezetsa magazi ndi Njira Mu situ kupanga silika fibroin gel osakaniza zida
Category Zida / m'tengo
fomu gel osakaniza zida
gwero Degummed Bombyx Mori  amakhala
Njira yosungirako  Yosungirako wouma mpweya wokwanira malo firiji
ndende zosiyanasiyana 1-30%
gelling Time 30 Mph
Bioburden Chosawilitsidwa (pa zigawo zikuluzikulu)
Tsiku lothera ntchito miyezi 18

A pplication: 

  Mu situ-n'kupanga ndi injectable silika hydrogel angagwiritsidwe ntchito ngati mankhwala ndi yobereka selo chonyamulira cha researches mu minofu zomangamanga / kukonza ndi yobereka mankhwala. The mankhwala ndi maselo adzaperekedwa kungakhale chisanadze wothira kusinthidwa silika fibroin njira kuphatikizapo zina ndi zigawo zina mwa zida kuti mofulumira kupanga hydrogel. Silika hydrogel ndi siyanitsa hydrogels ena biomaterial powapatsa kwambiri mawotchi mphamvu, mankhwala ndi kukhazikika thupi, biocompatibility ndi degradability. 




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